Test Catalog



Alternative Names: 5-HYDROXYTRYPTAMINE, SEROS, 4151, E800
Includes: Serotonin Serum
Sample Type: Serum
Preferred Container: Serum Separator Tube (SST)
Sample Volume: 1.0 mL
Minimum Volume: 0.3 mL
Handling Instructions: Spin and separate within one hour. Transfer 1 mL serum to a Standard Transport Tube.
Transport Temperature: Frozen
Specimen Stability: Frozen: 1 month
Testing Frequency: Sunday, Tuesday, Wednesday, Thursday, Friday
Expected Turn Around Time: Reference Lab
Testing Facility: ARUP
CPT Codes: 84260
Note: Abstain from medications for 72 hours prior to collection. Medications that may affect serotonin concentrations include lithium, MAO inhibitors, methyldopa, morphine, and reserpine. In general, foods that contain serotonin do not interfere significantly. Slight increases may be seen in acute intestinal obstruction, acute MI, cystic fibrosis, dumping syndromes, and nontropical sprue. Metastasizing abdominal carcinoid tumors often show serotonin concentrations greater than 400 ng/mL.

In general, EDTA whole blood (as compared to serum) preserved with ascorbic acid will give values most representative of blood concentrations. Most (95 percent) of blood serotonin is found in platelets.